OVERVIEW:
| Monoclonal TNFRSF11B antibody, Anti-TNFRSF11B antibody, Osteoprotegerin antibody, OPG antibody, OCIF antibody, osteoclastogenesis inhibitory factor antibody, TR1 antibody, TNFRSF11B, TNFRSFB 11, TNFRSFB-11, TNFRSFB 11 antibody, TNFRSFB-11 antibody |
| Human |
| ELISA, IF, IHC, WB |
| TNFRSF11B antibody was raised in Mouse using a purified recombinant fragment of human TNFRSF11B expressed in E. coli as the immunogen. |
SPECIFICATIONS:
| Mouse |
| 5G2 |
| IgG1 |
| Supplied as a liquid in ascitic fluid containing 0.03% sodium azide. |
| 1.0 mg/ml |
STORAGE & SAFETY:
| Store at 4 deg C for short term storage. Store at -20 deg C for long term storage. Avoid repeated freeze/thaw cycles. |
Usage Assay Information:
| ELISA: 1:10,000, IF: 1:200-1:1000, IHC: 1:200-1:1000, WB: 1:500-1:2000 |
GENERAL INFORMATION:
| TNFRSF11B is a member of the TNF-receptor superfamily. This protein is an osteoblast-secreted decoy receptor that functions as a negative regulator of bone resorption. TNFRSF11B specifically binds to its ligand, osteoprotegerin ligand, both of which are key extracellular regulators of osteoclast development. Studies of the mouse counterpart also suggest that this protein and its ligand play a role in lymph-node organogenesis and vascular calcification. |
